Resistance can spread even without the use of antibiotics

The decreased efficacy of antibiotics is a global problem and hinders the therapeutic outcome of previously treatable bacterial infections. In Europe, 33 000 people are estimated to die due to antibiotic resistant bacterial infections annually. Furthermore, these bacteria cause notable financial losts, for example in animal husbandry. In her doctoral dissertation at University of Jyvaskyla Pilvi Ruotsalainen developed mobile ”gene-scissors” which target and destroy antibiotic resistance genes and prevent their spread in bacterial communities. Due to largely diminished pipeline for the development of new antibiotics, alternative treatments are urgently needed against antibiotic resistant bacterial infections. PhD candidate Pilvi Ruotsalainen developed mobile ”gene-scissors” (CRISPR-Cas9) which target specifically different antibiotic resistance genes. These mobile ”gene-scissors” can spread from one bacterium to another in bacterial communities and destroy encountered antib

Resistance can spread even without the use of antibiotics

Antibiotic resistance does not spread only where and when antibiotics are used in large quantities, ETH researchers conclude from laboratory experiments. Reducing antibiotic use alone is therefore ...

Thu 5 Sep 19 from Medical Xpress

Molecular scissors technique to prevent the spread of antibiotic resistance genes in bacterial communities 

The decreased efficacy of antibiotics is a global problem and hinders the therapeutic outcome of previously treatable bacterial infections. In Europe, an estimated 33,000 people die due to antibiotic ...

Mon 2 Sep 19 from Medical Xpress

Mobile “gene-scissors” target to prevent the spread of antibiotic resistance genes in bacterial communities , Fri 30 Aug 19 from AlphaGalileo

Cholera bacteria have become highly drug-resistant

The bacteria have become resistant to all commonly used antibiotics. The highest resistance was against sulfamethaxozole

Sat 31 Aug 19 from The Hindu

Evolution of antibiotic resistance in E. coli studied

Bacteria form biofilms when exposed to low concentrations of antibiotic

Sat 31 Aug 19 from The Hindu

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