Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome

Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01764-9Inflammasomes are protein complexes that fight infection by driving inflammation or cell death. It now seems that the protein NEK7 provides a ‘licence’ for the formation of inflammasomes containing the protein NLRP3.

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome

Nature, Published online: 12 June 2019; doi:10.1038/s41586-019-1295-zA cryo-electron microscopy structure of human NLRP3 in complex with the mitotic kinase NEK7 provides insights ...

Wed 12 Jun 19 from Nature News

A licence to kill during inflammation

Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01764-9Inflammasomes are protein complexes that fight infection by driving inflammation or cell death. It now ...

Wed 12 Jun 19 from Nature News

Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

Nature, Published online: 12 June 2019; doi:10.1038/s41586-019-1307-zCryo-electron microscopy structures of the yeast 60S ribosomal subunit in complex with Vms1 provides insights ...

Wed 12 Jun 19 from Nature News

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