Analysis reveals key gene for bacterial infection

Researchers at Osaka University applied molecular evolutionary analysis to quantify the severity of negative selection pressures on genes encoding the pneumococcal choline-binding proteins (CBPs). They found particularly strong selective constraints on the gene cbpJ, suggesting its importance for bacterial infection. Further analyses revealed its role in bacterial evasion of host neutrophils, suggesting CbpJ's value as a target for drugs against streptococci.

Winning the arms race: Analysis reveals key gene for bacterial infection

Researchers have applied molecular evolutionary analysis to quantify the severity of negative selection pressures on genes encoding the pneumococcal choline-binding proteins (CBPs). They found ...

Mon 11 Mar 19 from ScienceDaily

Winning the arms race: Analysis reveals key gene for bacterial infection, Mon 11 Mar 19 from Eurekalert

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