Tricking bacteria into hydroxylating benzene

Researchers at Nagoya University used bacteria to convert benzene into phenol. They developed 'decoy' molecules -- modified amino acids -- mimicking the native substrates of a genetically expressed oxygenase enzyme. When absorbed by live E.coli cells, the decoys were misrecognized as substrates of the oxygenase, which became activated. The bacteria then oxidized a supplied benzene source, needing only glucose as fuel.

Tricking bacteria into hydroxylating benzene

Nagoya University researchers use E.coli to convert benzene into phenol, simplifying a chemical reaction that is difficult by conventional methods

Mon 11 Jun 18 from Phys.org

'Tricking' bacteria into hydroxylating benzene, Mon 11 Jun 18 from Eurekalert

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