A signaling pathway that restricts cleavage furrow formation to the mid-plane of the cell

Cell division is a fundamental biological process which ensures that, following the replication of the mother cell's genome, the two sets of chromosomes are equally distributed between two daughter cells. Chromosomes are segregated by the spindle apparatus, which is made up of fibrous protein structures called microtubules. The spindle apparatus is anchored to the opposite poles of the cell and determines the position of the future cleavage site in the middle of the cell, where a contractile protein ring is assembled. LMU researchers led by cell biologist Dr. Esther Zanin, who heads an Emmy Noether Research Group at the LMU Biocenter, have identified a molecular signaling pathway that restricts formation of the contractile ring to the mid-plane of the mother cell.

A signaling pathway that restricts cleavage furrow formation to the mid-plane of the cell

Cell division is a fundamental biological process which ensures that, following the replication of the mother cell's genome, the two sets of chromosomes are equally distributed between two daughter ...

Wed 10 Jan 18 from Phys.org

Cell biology: Positioning the cleavage furrow

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a signaling pathway that restricts cleavage furrow formation to the mid-plane of the cell.

Thu 11 Jan 18 from Eurekalert

Cell biology: Positioning the cleavage furrow, Thu 11 Jan 18 from AlphaGalileo

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