Computer redesigns enzyme

University of Groningen biotechnologists used a computational method to redesign aspartase and convert it to a catalyst for asymmetric hydroamination reactions. Their colleagues in China scaled up the production of this enzyme and managed to produce kilograms of very pure building blocks for pharmaceuticals and other bioactive compounds. This successful proof of principle study was published in Nature Chemical Biology on 21 May.

Computer redesigns enzyme

University of Groningen biotechnologists used a computational method to redesign aspartase and convert it to a catalyst for asymmetric hydroamination reactions. Their colleagues in China scaled ...

Mon 21 May 18 from Phys.org

Computer redesigns enzyme, Mon 21 May 18 from ScienceDaily

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